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Insulin Trouble Tied to Alzheimer's
胰岛素的麻烦与阿尔茨海默氏症
Study: Diabetes and Other Insulin Issues at Age 50 May Predict Alzheimer's Disease Decades Later
研究:糖尿病和其他胰岛素的问题,现年50岁,可以预测老人痴呆症十年后
April 9, 2008 -- People with diabetes or other insulin problems at age 50 may be especially likely to develop Alzheimer's disease decades later.
2008年4月9日-糖尿病的人或其他胰岛素问题, 5 0岁,可特别容易开发阿尔茨海默病的几十年以后。
That news comes from a Swedish study of more than 2,200 men followed for up to 35 years, starting at age 50.
这个消息来自一个瑞典研究2200多男子尾随,为长达35年,从50岁起。
"Our results suggest a link between insulin problems and the origins of Alzheimer's disease and emphasize the importance of insulin in normal brain function," Elina Ronnemaa, MD, of Sweden's Uppsala University, says in a news release. "It's possible that insulin problems damage blood vessels in the brain, which leads to memory problems and Alzheimer's disease, but more research is needed to identify the exact mechanisms."
"我们的研究结果表明,连接胰岛素问题,以及起源的阿尔茨海默氏症和强调的重要性胰岛素在正常的脑功能, " elina伦内马,海事处,瑞典的乌普萨拉大学,在一份新闻稿。 "这可能是胰岛素问题,损害血管,在大脑中,从而导致记忆问题与阿尔茨海默氏病,但需要进行更多的研究,以找出确切的机制" 。
When the Swedish study started, the men took fasting glucose tests to show how well their body used insulin, a hormone that controls blood sugar.
当瑞典的研究工作展开后,通常男性空腹血糖测试,以查看如何好他们的身体对胰岛素的利用,激素控制血糖。
Men who had a weaker insulin response to that test were 31% more likely to be diagnosed with Alzheimer's disease later in life, regardless of other factors such as age, BMI (body mass index), and education level.
男子,他们有一个较弱的胰岛素反应,以测试分别为31 %更有可能被诊断患有老年痴呆症的疾病后,在现实生活中,不论其他因素,如年龄, BMI (身体质量指数) ,以及教育程度。
That pattern applied to men with and without diabetes; it was strongest among men without the Alzheimer's-related APOE4 gene variation.
这种模式适用于男人和无糖尿病,它是最强的男人没有alzheimer's相关, ApoE4基因变异。
The findings, published in today's online edition of Neurology, follow a study released in 2007 linking poorly controlled diabetes to Alzheimer's disease and other research on the link between diabetes and Alzheimer's disease.
调查结果刊登在今天的网络版的神经病学,后续研究,在2007年发布,连接控制不佳糖尿病对阿尔茨海默氏症和其他研究之间的联系,糖尿病和老年痴呆症。
However, there are other risk factors for Alzheimer's disease, and as the Swedish researchers point out, it will take more work to put together all the pieces of the puzzle.
然而,也有其他危险因素的老年痴呆症,并作为瑞典的研究人员指出,将采取更多的工作放在一起,所有曲目的未解之谜。
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