Two-hour Glucose Levels Predict Hypertension
Bruce Goldfarb
澳大利亚糖尿病、肥胖和生活方式研究中心(AusDiab)的数据表明,餐后2hr血糖水平似乎能在未来5年内提高患者患高血压的风险。这是对餐后血糖水平是心血管的重要危险因素又提供新的证据。
New evidence suggests that postprandial glucose levels may be key to cardiovascular risk. High 2-hour plasma glucose (2hPG) levels appear to raise the risk of developing hypertension within 5 years, according to an analysis of data from the Australian Diabetes, Obesity, and Lifestyle. Study (AusDiab).
People with an average 2hPG of 115 mg/dl were about 36% more likely to develop hypertension within 5 years than those with an average 2hPG of 103 mg/dl, according to results presented at the European Association for the Study of Diabetes annual meeting, held September 18–21 in Amsterdam.
AusDiab involved 4,306 participants, with an average age of 47, who had a detailed medical exam and blood tests to measure glycemia and insulin levels. Over 5 years, 14% of the participants developed hypertension, defined as a pressure of
140 mmHg for systolic and
90 mmHg for diastolic.
研究数据表明,在5年的研究中,餐后2hr血糖与高血糖之间存在平滑的线性关系。即使在正常范围内,餐后2hr血糖水平越高也与更高的血压水平相关联。
Analysis of data showed a smooth linear relationship between 2hPG and hypertension over the 5-year period, with higher blood pressure associated with higher 2hPG even in the normal 2hPG range.
Interventions aimed at reducing the 2hPG level may "potentially yield additional benefits through reduction in hypertension," according to Elizabeth Barr, MPH, an epidemiologist at the International Diabetes Institute in Melbourne, Australia.