一型移植猪细胞10年仍在发挥作用

金玲

10 years on, pig cells still fighting diabetes
•        Leigh Dayton
•        April 02, 2007
Michael Helyer suspected the pig cells in his abdomen were still alive 10 years after they were injected, because they were occasionally cranking out enough insulin to help control his blood sugar levels.
The effect "would come and go -- that's why I noticed it", said the 51-year-old who was diagnosed with Type I, or juvenile, diabetes at age 22.
He was right, surprising scientists and paving the way for new long-term treatments for diabetes that reduce the need for insulin injections.
"I was astonished," said New Zealand-based diabetes researcher Bob Elliott, founder and medical director of Living Cell Technologies, with headquarters in Melbourne.
He said he expected the transplanted cells to live six months to a year.
According to Professor Elliott, more advanced versions of Mr Helyer's pig cell therapy could be available within two years if planned human trials in New Zealand and Russia are successful.
The trials cannot be run in Australia because animal-to-human transplants (xenotransplants) were halted in 2004 under a five-year moratorium established by the National Health and Medical Research Council.
The NHMRC feared animal diseases could be transplanted along with the tissue.
But Professor Elliott said his firm has side-stepped the problem by breeding a disease-free herd based on pigs isolated for 200 years on the sub-Antarctic Auckland Islands. The animals were originally put ashore by sailors as a living larder.
"This has never been done before," said Professor Elliott. "It's a profound step forward for safe, effective and long-term diabetes control."
(The Australian, April 2 2007) 《澳洲人报》4月2日

[ 本帖最后由 金玲 于 2007-4-2 18:29 编辑 ]

霍去病

内心等待

牛牛

请给翻译一下，看不懂。谢谢

约翰尼德普

迈克尔helyer疑为猪细胞腹部10年后仍健在注射, 因为他们偶尔写下足够的胰岛素帮助他控制血糖水平. 扣除"出没--这也是为什么我注意到它" 说51岁被诊断患有I型或少年,糖尿病在22岁以下. 他是对的, 奇怪的科学家和新铺平长期治疗糖尿病,减少需要注射胰岛素. "我感到很惊讶,说:"新西兰的鲍勃糖尿病研究员Elliott女士、医务主任、创始人活细胞技术 总部设在墨尔本. 他说,他预期活细胞移植六个月至一年. 据教授Elliott女士、 郑helyer版本更先进的猪细胞疗法可望在两年内如果人体试验计划 新西兰和俄罗斯是成功的. 审判不能办,因为澳洲动物对人类器官移植(xenotransplants)2004年被迫停顿下一个五年暂缓成立 由国家卫生和医学研究理事会. nhmrc害怕的动物传染病可随着组织移植. 但是教授说他的公司已经Elliott女士避问题滋生了无病的猪只隔离畜群 200年的分南极奥克兰群岛. 动物原本提出为水手上岸打猎为生. "这前无古人"教授Elliott女士. "这是一场深刻的一步,为安全有效和长期糖尿病控制"